Our database can be accessed through WCF (SOAP over HTTP) or through RESTful (JSON over HTTP) services.
The WCF service for searching directed genic interactions is located at http://literome.cloudapp.net:8080/NetworkService.svc.
The service for searching genotype-phenotype associations is at http://literome.cloudapp.net:8080/GwasService.svc.
The RESTful service for searching directed genic interactions is located at http://literome.cloudapp.net/network/get, and requires parameters gene1 and gene2. So to search for interactions between ABL1 and CTNNB1, send a POST request to http://literome.cloudapp.net/network/get?gene1=abl1&gene2=ctnnb1.
The service for searching genotype-phenotype associations is at http://literome.cloudapp.net/gwas/get, and requires parameters snporgene and diseaseordrug. So to search for associations between ABL1 and breast neoplasms, send a POST request to http://literome.cloudapp.net/gwas/get?snporgene=abl1&diseaseordrug=breast%20neoplasms.
Sample Code (WCF and REST)
Download the LiteromeServiceClient source code for examples of how to access all of the above services.
"Literome: PubMed-Scale Genomic Knowledge Base in the Cloud"
Hoifung Poon, Chris Quirk, Charlie DeZiel, David Heckerman
In Bioinformatics 30.19 (2014), 2840-2842.